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Frankie Pamplemousse, an energetic 8-year-old girl, lives in Anytown with her four talking, extraordinary hamsters; Pipsqueak, Mr. Squiggles, Num Nums, and Chunk.
Frankie and the Zhus try to make Ellen and Stanley's anniversary a blast by planning their own.
The Zhus get stuck in the wild after a skunk shows up in their house.
After Frankie's baseball glove is accidentally left at home, the Zhus try to return it back to her before her big game starts.
Ellen tells the Zhus that they can't go to the grocery store, but they break the rule after Chunk eats all of the chocolate chips.
While getting her dog Walter a snack, Frankie asks the Zhus to dog-sit him. But they accidentally let Walter out the backyard.
The Zhus try to make friends with Mr. Kerdle, while Frankie tries to stop them from getting in trouble.
Frankie is told she can't plumb with her parents on a level 5 job for professionals only. When the Zhus give Frankie something to do, a pipe snaps and the entire house floods.
Frankie is offered a deal to appear on television to show off her skateboarding skills, but Chunk gets carried away when giving her a makeover.
Frankie and the Zhus think that the Gelato twins have turned into zombies after watching a zombie film during a sleepover.
Frankie is sick and can't go to the Go-Kart race, so the Zhus try to help her get better in time.
Num Nums gets taken by Madge's cat, so the Zhus try to rescue her while Frankie distracts Madge.
Frankie and the Zhus try to get on a TV show called World's Funniest Pets.
A rainy day prevents the Zhus from doing the Iron Hamster Games, until Frankie decides to do it inside.
Frankie and the Zhus pretend to be superheroes, but Mr. Squiggles takes his role as the villain too seriously.
Frankie and the Zhus take care of a baby bird and teach it to fly.
When Frankie gets two friendship bracelets from her aunt Zia, the Zhus compete to see who is Frankie's best friend.
Frankie's parents get an emergency plumbing call from Frankie's favorite popstar Jessica Beeker. They take Frankie and the Zhus with them to meet Jessica, but Frankie becomes nervous.
Frankie and the Zhus try to help Ellen get her last Power Badge Girls badge, the camping badge, when they learn she's afraid of the dark.
The Zhus help Frankie decide what she wants to be when she grows up for a school project.
When Frankie breaks her fourth skateboard, her parents cut a deal that she can get another if she goes a week without breaking an egg.
