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Coming again. For the last time.
Teenage friends find their lives upended by the wonders and horrors of puberty in this edgy comedy from real-life pals Nick Kroll and Andrew Goldberg.
With a big dance approaching, FOMO's everywhere: Missy misses school, Matthew dives into the deep end — and Andrew suspects that Other Andrew is evil.
Jessi and Jay pair up to parent a melon "baby," Missy faces her fears, and Nick and Other Andrew try to fit in with a group of ultra-rich kids.
After Nick has a sudden growth spurt, Ms. Dunn takes the class inside the body of a teenager to learn about the wonders of puberty.
A reckless Lola gets behind the wheel, and Jessi and her mom have a really big fight. Nick's mother finds his "special shirt" while cleaning his room.
Depression Kitty convinces an anxious Jessi to care less. Nick attracts Devin's attention, and the Robotics Club takes an overnight field trip.
Matthew explores his sexual preferences, Nick says the wrong thing, and Missy uses Andrew to make Nate jealous. Jessi finds a surprise on Camden's phone.
Connie recruits a Compassion Pachyderm to teach the kids how to see things from another point of view. Andrew sets out to steal Missy's man.
Missy's Lovebug steps in to solve a problem, and Jessi practices enthusiastic consent. Nick tries life without porn. Lola gives Jay's dog a makeover.
In honor of the show's next-to-last episode, Maury and Connie dive into the "Big Mouth" mailbag to answer curious fans' burning questions.
As the kids creep closer to adulthood, a memorable finale takes them back to where it all began to say goodbye — and face the future.
Nick Kroll
Nick Birch / Maury the Hormone Monster / Coach Steve / Lola Skumpy / Rick the Hormone Monster (voice)
John Mulaney
Andrew Glouberman (voice)
Jessi Klein
Jessi Glaser (voice)
Jason Mantzoukas
Jay Bilzerian (voice)
Maya Rudolph
Diane Birch / Connie the Hormone Monstress (voice)
Fred Armisen
Elliot Birch (voice)
Jordan Peele
Ghost of Duke Ellington (voice)
Andrew Rannells
Matthew (voice)
