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無限の住人
故事讲述了日本还在江户时代时的1792年，杀死了做恶的贪官上司，并在逃亡途中无意间杀死了前来追捕自己的妹夫，虽然万次想放下屠刀却不断被人追杀，还毁掉了妹妹的一生。 却由于被八百比丘尼埋进了血仙虫而拥有不死之身的剑士万次，为了解开血仙虫造成的不死之咒语，发誓杀一千个恶人来赎百人斩的罪。遇到身负血仇的孤女凛后，他决定帮助其报仇。 一路遭遇凛的仇人「逸刀流」、旨在剿灭逸刀流的幕府密探「无骸流」以及其他种种势力或个人。在无法界定对错的凛的复仇之旅中，万次打败了一个个强悍的对手——也许对他来说，千人斩的实现仅仅是时间的问题。 可是，剑客都是双手沾满鲜血的人，谁为善心，谁又为恶人，万次有鉴定的资格和能力吗？杀人，就是一种罪，杀恶人也是杀人，这世上真的有可以籍着杀人赎清的罪孽吗？每个人都只是为着自己的理由挥剑而已。 对于万次，在过去无可挽回的悔恨中许下了杀千人的悲愿，也许却只不过是继续挥刀活下去的理由，继续杀人的理由…… 也许，这不算是乱世——没有战国的烽火，没有维新的狂岚，德川幕府正安然的统治着一切，居高临下的睥睨着剑客之间的争斗，一步步的算计着可以驱使的力量。看起来，一切似乎都在某种控制之中。 德川幕府时代，江户城内有位背负着百条人命的杀手——万次。他拥有无限的生命、杀不死的身体，万次为了赎罪立誓要斩千个恶人。一个十六岁的少女——凛，她为了报血海深仇，找上万次当她的保镖去消灭「逸刀流」。 将万次囚禁在地牢内的番头，吐钩群的真正目的居然是想用医学的方法取得不死之身。 认定“只有胜利才是剑之王道”的逸刀流统主天津影久，残忍地杀害了少女凛的父母。凛和在身体里埋入血仙虫成为不死之身的百人斩男人万次卍一起，踏上了复仇的旅程……
Manji visits a priest in order to confess his sins, namely killing his lord and 100 of his retainers, an act that earned him the moniker "Killer of 100." The priest, who is actually a con artist, attempts to kill Manji by shooting him in the forehead, but Manji kills him and regenerates the wound. Manji returns to his home to find Yaobikuni, a nun who placed "sacred bloodworms" into Manji that make him immortal, and his sister Machi. That evening, Machi dreams of the time when Manji was forced to kill her husband, a police officer purusing Manji, causing her to lose her mind. After the dream, she wanders into the night and is captured by a group of ronin led by the brother of the priest Manji had killed. Manji pursues Machi but is unable to prevent her from being killed. In response, he kills every member of the ronin group, and upon returning to Yaobikuni, declares that he will seek redemption for the 100 men he killed by killing 1000 evil men.
More details about the tragic demise of Rin's family and their dojo are shown during her encounter with Manji. Members of the Ittō-ryū and the Mugai-ryū are introduced, too.
Manji's and Rin's fateful encounter with Sabato Kuroi. His relationship to Anotsu is further explored as well as the role of the members of the Mugai-ryū.
Rin tries in vain to hire Sori, an artist. His house is attacked by minions of the Ittō-ryū, which makes him reveal his true colors.
The tragic past of Taito Magatsu, another member of the Ittō-ryū, who is a target of Rin's vengeance, is revealed. He attempts to lead a normal life by leaving the Ittō-ryū, but encounters Rin and Manji.
Members of the Mugai-ryū are assassinated by members of the Ittō-ryū. Manji an Rin encounter Eiku Shizuma, who reveals Manji's and weakness.
Manji settles the score with Shizuma and receives information about Anotsu's whereabouts.
Rin and Manji encounter Makie Otono-Tachibana, whose life Manji spares, since she appears to be too weak to pose a threat. Furthermore her relationsship to Anotsu is explored.
More details from Anotsu's and Makie's past are revealed. A fierce battle between Manji and Makie unfolds. Afterwards the latter leaves Anotsu and the Ittō-ryū.
Rin and Manji encounter Araya Kawakami, one of the men who raped Rin's mother. His past is revealed and after Rin bravely saves his son, she goes unarmed to his house.
Rin confronts Kawakami emotionally, but is assaulted by him. Manji comes to her rescue and exacts her vengeance. Rin succeeds in foiling his son's plan to continue living for revenge only.
Manji and Rin travel to the house where he lived with his sister and he continues to train Rin. During a break she encounter Anotsu in a nearby forest. After her futile assassination attempt he discloses to Rin the reasons for the animosity between her father and him.
The paths taken by all the surviving characters are shown. Rin abolishes her hesitations and trains with utter devotion. Meanwhile the tactics of the Mugai-ryū seem to have sealed Anotsu's fate.
